-Third AREVA-Pasteur Forum on Mosquito- and Tick-Borne Viruses and thier Environment, June 12-14, 2008, Institut Pasteur Shangai - Chinese Academy of Sciences - Arthropod-borne viruses (Arboviruses) are dangerous pathogens for animal and humans which may cause acute diseases with high burden for human activities.In 30 years, knowledge on arboviral biology, host-pathogen interaction, host responses, innate immunity, and host genetic susceptibility has made invaluable progress, opening new avenues for innovation on virus structure and morphogenesis, viral protein function, mechanisms of viral- and immuno-pathogenesis, virus-vector interactions, vaccine, and drug discovery.
The scientific programme will largely cover complementary aspects including: I. Emergence and control of arboviruses (factors, virus evolution, climate change, epidemiology II. Virus biology (structure, entry, replication, morphogenesis….) III. Virus-host interaction (receptors, protein-protein interaction, arthropod biology and virus persistence…) IV. Animal and ex-vivo models and pathogenesis (knock-out mice, hamsters, vascular permeability…) V. Immune response and protection (signalization, innate immunity, acquired immunity, cross-protection, vaccine…) VI. Anti-viral strategies (drug discovery, serotherapy…)
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