top of page
HKU-Pasteur Research Pole_Master Logo_BlackLARGE-01.png

Chris Mok’s Work On Cross-Reactive Antibody Response Between SARS-CoV-2 And SARS-CoV Infections

  • Writer: ITS HKU
    ITS HKU
  • May 19, 2020
  • 1 min read

Published In Cell Reports And featured On EurekAlert!


EurekAlert!, operated by AAAS, has featured a publication from Chris Mok's team on Cross-Reactive Antibody Response Between SARS-CoV-2 And SARS-CoV Infections published in Cell Reports.

Patients infected with either severe acute respiratory syndrome coronavirus (SARS-CoV) or SARS-CoV-2 produce antibodies that bind to the other coronavirus, but the cross-reactive antibodies are not cross protective, at least in cell-culture experiments, researchers report May 17 in the journal Cell Reports. It remains unclear whether such antibodies offer cross protection in the human body or potentiate disease. The findings suggest that more research is needed to identify parts of the virus that are critical for inducing a cross-protective immune response.

"Since coronavirus outbreaks are likely to continue to pose global health risks in the future, the possibility of developing a cross-protective vaccine against multiple coronaviruses has been considered," says co-senior study author Chris Mok of the University of Hong Kong. "Our findings, albeit limited at present, would suggest that broadly cross-neutralizing antibodies to coronaviruses might not be commonly produced by the human immune repertoire. Moving forward, monoclonal antibody discovery and characterization will be crucial to the development of a SARS-CoV-2 vaccine in the short-term, as well as a cross-protective coronavirus vaccine in the long term. [...]"


Comments


CONTACT

 

Tel:              (852) 2831 5494

Fax:             (852) 2872 5782

Email:          hku-pasteur@hku.hk

Address:      7/F, Room 705, Hong Kong Jockey Club Building

                      For Interdisciplinary Research
                      5 Sassoon Road, Pokfulam, Hong Kong SAR

HKU-Pasteur Research Pole_Master Logo_White.png
  • Twitter
  • Facebook
  • Instagram
  • LinkedIn
  • Youtube

© 2021 HKU-Pasteur Research Pole

bottom of page