Dr Suki Lee, principal investigator at HKU-Pasteur Research Pole, and her team have recently published a review paper in Frontiers in Immunology to discuss the latest advancements in novel host-based approaches with potential for influenza treatment.
Viruses rely on host cellular functions to replicate, recent therapeutic developments focus on targeting host factors involved in virus replication. Besides controlling virus replication, virus-induced host immune response, such as the latest ideas suggesting the involvement of innate lymphoid cells and NADPH oxidases in influenza virus pathogenesis as well as the renewed interest in immune cell metabolism may serve as potential targets for drug development.
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