25 Nov 2015

Road to COP21: climate change and one-health strategy, the role of HKU-Pasteur Research Pole

Through interdisciplinary research and international teaching programs, HKU-Pasteur Research Pole will take an active part in the Center for Global Health instigated by Institut Pasteur to respond to the current health challenges in a globalized context. Oriented toward a "One-Health" approach, the Pasteur Center for Global Health includes climate change pressure.

Climate change is a major threat to global health in the 21st century with growing impacts of climate on human populations. One of these impacts relates to outbreaks of infectious diseases. Changes in temperature and precipitation affect vectorborne and zoonotic diseases, modifying pathogen-host interaction, ecosystems and species composition or distribution.

As the determinants of health are converging and interventions are increasingly interdependent, analyses and responses to current global threats require a concerted global approach including climate change issue and improved understanding of major global health challenges through research and public health actions.

For Institut Pasteur, the grand challenge is now to set up a new global paradigm that will be able to enhance human, animal and environmental health by developing multi-disciplinary research projects of international excellence through the integration of basic, clinical and epidemiological research spanning the animal-human-environment interface, i.e. an inclusive One-Health approach, fostered by the creation of the Pasteur Center for Global Health.

As the hub of the Institut Pasteur International Network in Asia, HKU-Pasteur Research Pole (HKU-PRP) takes part in this approach.

Focusing on the interface between humans and the environment, comprising animals and microbes,  HKU-PRP will develop interdisciplinary research projects to improve knowledge of diseases and promote transformative discoveries that will impact the most affected populations.  Besides  strengthening synergy between research and education by establishing a comprehensive training program,  HKU-PRP will reinforce scientific knowledge and technical skills to train and equip the next generation of  researchers and global health leaders.

You can download our booklet presenting the main objectives of HKU-PRP here.

Visit the Pasteur Center for Global Health (CGH) website, please follow this link.

25 Nov 2015

Congratulations to Mingyuan Li and Ooiean Teng on completing their PhD!

Mingyuan Li and Ooiean Teng, former PhD students from the HKU-Pasteur Research Pole, have been awarded the degree of Doctor of Philosophy at the University of Hong Kong, Li Ka Shing Faculty of Medicine, School of Public Health, on November 21, 2015.

Mingyuan Li's thesis is entitled "Molecular Dissection of Dengue Virus Egress: Involvement of Host Cellular Factors-KDEL receptors". Her studies have uncovered a new function for KDEL receptors in the intracellular trafficking of the de dengue virus and identified a rate-limiting molecular step in the late stages of the dengue virus life cycle. Her work had been supervised by Prof. Roberto Bruzzone (principal supervisor) and Dr. Michael Chi Wai Chan (co-supervisor).

Mingyuan Li during the 194th Congragation and Prize Presentation Ceremony in Lee Shau Kee Lecture Centre, Centennial Campus, HKU

Ooiean Teng's work is entitled "Identification of CLEC5A in Modulating Host Immune Response after Influenza A Virus Infection". Her thesis work has shown that CLEC5A (C-Type Lectin Domain Family 5 Member A, transmembrane receptor) is a host factor for influenza pathogenesis by modulating host innate inflammatory response. She had been supervised by Dr. Hui-Ling Yen (principal supervisor) and Prof. Roberto Bruzzone (co-supervisor).

Ooiean Teng (left) and Mingyuan Li (right) with Prof. Roberto Bruzzone (middle) after the ceremony

Congrats Dr Mingyuan and Dr Ooiean!

11 Nov 2015

In Memoriam: Prof Li-chong Chan

In Memoriam: Prof Li-chong Chan

It is with great sadness that we announce that Professor Li-chong Chan passed away on Sunday, November 8th, 2015.

Professor Chan served on the Board of Directors of HKU-Pasteur between 2007 and 2013 and was a strong supporter of this collaborative program.

Professor Chan joined HKU in 1989 and led the Department of Pathology as Head between 2002 to 2011.

He was a humanist, a man of great culture and was the driving force in establishing the Center of Humanities and Medicine at HKU.  LC, as he was known to friends and colleagues was Director of the Faculty's Medical Ethics and Humanities Unit.

Professor Chan had made significant contributions to the field of pathology, medical education and the whole of the medical community in Hong Kong at large.  He will be sorely missed and warmly remembered by all those who knew him.