Research

Researches

Publications

Year 2012

Yang L, Chan KP, Lee RS, Chan WM, Lai HK, Thach TQ, Chan KH, Lam TH, Peiris JS, Wong CM.

Obesity and influenza associated mortality: Evidence from an elderly cohort in Hong Kong.

Prev Med. 2012 Dec 4. pii: S0091-7435(12)00594-4. doi: 10.1016/j.ypmed.2012.11.017. [Epub ahead of print]. PMID: 23219760.

Chan RW, Leung CY, Nicholls JM, Peiris JS, Chan MC.

Proinflammatory Cytokine Response and Viral Replication in Mouse Bone Marrow Derived Macrophages Infected with Influenza H1N1 and H5N1 Viruses.

PLoS One. 2012;7(11):e51057. doi: 10.1371/journal.pone.0051057. Epub 2012 Nov 30. PMID: 23226456.

Millet JK, Kien F, Cheung CY, Siu YL, Chan WL, Li H, Leung HL, Jaume M, Bruzzone R, Peiris JSM, Altmeyer RM, Nal B.

Ezrin Interacts with the SARS Coronavirus Spike Protein and Restrains Infection at the Entry Stage.

PLoS ONE: Research Article, published 21 Nov 2012 10.1371/journal.pone.0049566. PMID: 23185364.

Tang DJ, Lam YM, Siu YL, Lam CH, Chu SL, Peiris JS, Buchy P, Nal B, Bruzzone R.

A Single Residue Substitution in the Receptor-Binding Domain of H5N1 Hemagglutinin Is Critical for Packaging into Pseudotyped Lentiviral Particles.

PLoS One. 2012;7(11):e43596. doi: 10.1371/journal.pone.0043596. Epub 2012 Nov 2. PMID: 23133587.

Yang L, Wang X, Chan K, Cao P, Lau H, Peiris J, Wong C.

Hospitalisation associated with the 2009 H1N1 pandemic and seasonal influenza in Hong Kong, 2005 to 2010.

Euro Surveill. 2012 Nov 8;17(45). pii: 20309. PMID: 23153475.

Chu DK, Leung CY, Perera HK, Ng EM, Gilbert M, Joyner PH, Grioni A, Ades G, Guan Y, Peiris JS, Poon LL.

A novel group of avian astroviruses in wild aquatic birds.

J Virol. 2012 Oct 3. [Epub ahead of print]. PMID: 23035212.

Lee SM, Yen HL.

Targeting the host or the virus: current and novel concepts for antiviral approaches against influenza virus infection.

Antiviral Res. 2012 Sep 26. pii: S0166-3542(12)00215-X. doi: 10.1016/j.antiviral.2012.09.013. [Epub ahead of print]. PMID: 23022351.

Mesel-Lemoine M, Millet J, Vidalain PO, Law H, Vabret A, Lorin V, Escriou N, Albert ML, Nal B, Tangy F.

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes.

J Virol. 2012 Jul;86(14):7577-87. Epub 2012 May 2. PMID: 22553325.

Wong CM, Yang L, Chan KP, Chan WM, Song L, Lai HK, Thach TQ, Ho LM, Chan KH, Lam TH, Peiris JS.

Cigarette smoking as a risk factor for influenza-associated mortality: evidence from an elderly cohort.

Influenza Other Respi Viruses. 2012 Jul 20. doi: 10.1111/j.1750-2659.2012.00411.x. [Epub ahead of print] PMID: 22813463.

Wang XL, Yang L, Chan KP, Chiu SS, Chan KH, Peiris JS, Wong CM.

Model selection in time series studies of influenza-associated mortality.

PLoS One. 2012;7(6):e39423. Epub 2012 Jun 20. PMID: 22745751.

Wong DD, Choy KT, Chan RW, Sia SF, Chiu HP, Cheung PP, Chan MC, Peiris JS, Yen HL.

Comparable fitness and transmissibility between oseltamivir-resistant pandemic 2009 and seasonal H1N1 influenza viruses with the H275Y neuraminidase mutation.

J Virol. 2012 Jul 18. [Epub ahead of print]. PMID: 22811535.

Lee SM, Dutry I, Peiris JS.

Editorial: Macrophage heterogeneity and responses to influenza virus infection.

J Leukoc Biol. 2012 Jul;92(1):1-4. PMID: 22745457.

Yen HL, Peiris JS.

Virology: bird flu in mammals.

Nature. 2012 May 2;486(7403):332-3. PMID: 22722190.

Chao B, Tong XK, Tang W, Li DW, He PL, Garcia JM, Zeng LM, Gao AH, Yang L, Li J, Nan FJ, Jacobs M, Altmeyer R, Zuo JP, Hu YH.

Discovery and Optimization of 2,4-Diaminoquinazoline Derivatives as a New Class of Potent Dengue Virus Inhibitors.

J Med Chem. 2012 Mar 26. [Epub ahead of print]. PMID: 22448770.

Wang XL, Yang L, Chan KP, Chiu SS, Chan KH, Peiris JS, Wong CM

Model selection in time series studies of influenza-associated mortality.

PLoS One. 2012;7(6):e39423. doi: 10.1371/journal.pone.0039423. Epub 2012 Jun 20.

Tang DJ, Lam, YM, Siu YL, Lam CH, Chu SL, Peiris JS, Buchy P, Nal B, Bruzzone

A single amino acid substitution in the 130-loop of the receptor-binding domain of H5N1 hemagglutinin is critical for efficient packaging into pseudotyped lentiviral particles.

PLoS One. 2012;7(11):e43596. doi: 10.1371/journal.pone.0043596. Epub 2012 Nov 2.

Qiao C, Liu Q, Bawa B, Shen H, Qi W, Chen Y, Mok CK, García-Sastre A, Richt JA, Ma W

Pathogenicity and transmissibility of reassortant H9 influenza viruses with genes from pandemic H1N1 virus.

J Gen Virol. 2012 Nov;93(Pt 11):2337-45. doi: 10.1099/vir.0.044040-0. Epub 2012 Aug 8.

Kudelko M, Brault JP, Kwok K, Li MY, Pardigon N, Peiris JS, Bruzzone R, Desprès P, Nal B, Wang PG

Class II ADP-ribosylation factors are required for efficient egress of dengue viruses.

J Biol Chem. 2012 Jan 2;287(1):767-77. doi: 10.1074/jbc.M111.270579. Epub 2011 Nov 21.

Jaume M, Yip MS, Kam YW, Cheung CY, Kien F, Roberts A, Li PH, Dutry I, Escriou N, Daeron M, Bruzzone R, Subbarao K, Peiris JS, Nal B, Altmeyer R.

SARS CoV subunit vaccine: antibody-mediated neutralisation and enhancement.

Hong Kong Med J. 2012 Feb;18 Suppl 2:31-6. PMID 22311359.

Lai JC, Garcia JM, Dyason JC, Böhm R, Madge PD, Rose FJ, Nicholls JM, Peiris JS, Haselhorst T, von Itzstein M.

A Secondary Sialic Acid Binding Site on Influenza Virus Neuraminidase: Fact or Fiction?

Angew Chem Int Ed Engl. 2012 Jan 26. doi: 10.1002/anie.201108245. [Epub ahead of print]. PMID: 22281708.

Fouchier RA, García-Sastre A, Kawaoka Y, Barclay WS, Bouvier NM, Brown IH, Capua I, Chen H, Compans RW, Couch RB, Cox NJ, Doherty PC, Donis RO, Feldmann H, Guan Y, Katz J, Klenk HD, Kobinger G, Liu J, Liu X, Lowen A, Mettenleiter TC, Osterhaus AD, Palese P, Peiris JS, Perez DR, Richt JA, Schultz-Cherry S, Steel J, Subbarao K, Swayne DE, Takimoto T, Tashiro M, Taubenberger JK, Thomas PG, Tripp RA, Tumpey TM, Webby RJ, Webster RG.

Pause on Avian Flu Transmission Research.

Science. 2012 Jan 27;335(6067):400-1. PMID 22282787

Chiu SS, Chan KH, So LY, Chen R, Chan EL, Peiris JS.

The population based socioeconomic burden of pediatric influenza-associated hospitalization in Hong Kong.

Vaccine. 2012 Jan 2. [Epub ahead of print]. PMID: 22222872.