Research

Researches

Publications

Year 2020

Saeed Behzadinasab, Alex Chin, Mohsen Hosseini, Leo L. M. Poon, William A. Ducker

A Surface Coating that Rapidly Inactivates SARS-CoV-2

ACS Appl. Mater. Interfaces 2020 ; doi.org/10.1021/acsami.0c11425

Thomas H. C. Sit, Christopher J. Brackman, Sin Ming Ip, Karina W. S. Tam, Pierra Y. T. Law, Esther M. W. To, Veronica Y. T. Yu, Leslie D. Sims, Dominic N. C. Tsang, Daniel K. W. Chu, Ranawaka A. P. M. Perera, Leo L. M. Poon & Malik Peiris

Infection of dogs with SARS-CoV-2

doi.org/10.1038/s41586-020-2334-5

Asmaa Hachim, Niloufar Kavian, Carolyn A Cohen, Alex WH Chin, Daniel KW Chu, Chris Ka Pun Mok, Owen TY Tsang, Yiu Cheong Yeung, Ranawaka APM Perera, Leo LM Poon, Malik JS Peiris, Sophie A Valkenburg

Beyond the Spike: identification of viral targets of the antibody response to SARS-CoV-2 in COVID-19 patients

doi: https://doi.org/10.1101/2020.04.30.20085670

Alex W H Chin, Julie T S Chu, Mahen R A Perera, Kenrie P Y Hui, Hui-Ling Yen, Michael C W Chan, Malik Peiris, Leo L M Poon

Stability of SARS-CoV-2 in different environmental conditions

doi.org/10.1016/ S2666-5247(20)30003-3

Yuan M, Wu NC, Zhu X, Lee CCD, So RTY, Lv H, Mok CKP, Wilson IA

A highly conserved cryptic epitope in the receptor-binding 4 domains of SARS-CoV-2 and SARS-CoV

Science, in press; bioRxiv doi/10.1101/2020.03.13.991570.

Wang Y, Li X, Liu W, Gan M, Zhang L, Wang J, Zhang Z, Zhu A, Li F, Sun J, Zhang G, Zhuang Z, Luo J, Chen D, Qiu S, Zhang L, Xu D, Mok CKP, Zhang F, Zhao J, Zhou R, Zhao J

Discovery of a subgenotype of human coronavirus NL63 associated with severe lower respiratory tract infection in China, 2018

Emerg Microbes Infect 9:246-255.

Valkenburg SA, Cowling BJ

Turning influenza vaccinology on its head to reveal the stalk

Lancet Infect Dis 20:5-7.

Kavian N, Hachim A, Li APY, Cohen CA, Chin AHW, Poon LLM, Fang VJ, Leung NHL, Cowling BJ, Valkenburg SA

Assessment of enhanced influenza vaccination finds FluAd advantage in mice and older adults

Clin Transl Immunol 9:e1107.

Cowling BJ, Perera RAPM, Valkenburg SA, Leung NHL, Iuliano AD, Tam YH, Wong JHF, Fang VJ, Li APY, So HC, Ip DKM, Azziz-Baumgartner E, Fry AM, Levine MZ, Gangappa S, Sambhara S, Barr IG, Skowronski DM, Peiris JSM, Thompson MG

Comparative immunogenicity of several enhanced influenza vaccine options for older adults: A randomized, controlled trial

Clin Infect Dis doi: 10.1093/cid/ciz1034. PMID: 31828291.

Jahan AS, Biquand E, Munoz-Moreno R, Le Quang A, Mok CK, Wong HH, Teo Q, Valkenburg SA, Chin AWH, Poon LLM, te Velthuis A, García-Sastre A, Demeret C, Sanyal S

OTUB1 is a key regulator of RIG-I-dependent immune signaling and is targeted for proteasomal degradation by influenza A NS1

Cell Rep 30:1570–1584.

Lv H, Wu NC, Tsang OT, Yuan M, Perera RAP, Leung WS, So RT, Chan JMC, Yip GK, Chik TSH, Wang Y, Choi CYC, Lin Y, Ng WW, Zhao J, Poon LLM, Peiris JSM, Wilson IA, Mok CKP

Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections

Cell Rep, doi: https://doi.org/10.1101/2020.03.15.993097.

Li MY, Naik TS, Siu LYS, Acuto O, Spooner E, Wang P, Yang X, Lin Y, Bruzzone R, Ashour J, Sanyal S

Activation of Src-family kinases orchestrate secretion of flaviviruses by targeting mature progeny virions to secretory autophagosomes

Nat Microbiol, in revision; bioRxiv doi: https://doi.org/10.1101/2020.01.12.903062