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    5th HKU-Pasteur Cell Biology Course

    Course Date: 13 Apr 2013

    for Research Postgraduate Students (MPhil and PhD)

    Programme (last update: 03/04/2013) / Open Public Lectures

    DATE:

    14 - 26 April 2013

    TOPIC:

    IMAGING HOST-PATHOGEN INTERACTIONS

    The major objective of this course is to present imaging technologies utilized to identify key steps involved in infection. The course will discuss the fundamental molecular mechanisms regulating cell polarization, protein sorting and trafficking, within the general framework of host-pathogen interactions and will present examples of cutting edge techniques utilized to visualize dynamic processes in living and fixed cells. The course will also highlight, at a theoretical level, how imaging and image analysis are heavily influencing the investigation of host-pathogen interactions, deciphering cellular pathways and architecture, and visual based screening approaches. Special attention will be paid to how cell based assays are developed to first identify the phenomenon, and then used to give robust and unambiguous results when screened.

    In the practical work, two bacterial pathogens (Shigella and Salmonella) will be used to demonstrate different aspects of the successive stages during host-pathogen interaction at the cellular level such as motility, cell contact, uptake, intracellular survival and modulation of host gene response. Participants will use the data from cell-based assays and apply image processing algorithms to discriminate differing stages in infection. Participants will learn how to use ImageJ as a versatile tool for image analysis and discuss different commercially available as well as custom made software.

    DIRECTORS:

    • Roberto BRUZZONE, HKU-Pasteur Research Centre
    • Chiara ZURZOLO, Institut Pasteur
    • George TSAO, University of Hong Kong

    LECTURERS:

    • Roberto BRUZZONE, Hong Kong
    • Jost ENNINGA, France
    • Urs GREBER, Switzerland
    • Nancy GUILLEN, France
    • Ludger JOHANNES, France
    • Tom KIRCHHAUSEN, USA
    • Mark MARSH, UK
    • Musa MHLANGA, South Africa
    • Rob PARTON, Australia
    • Agneta RICHTER-DAHLFORS, Sweden
    • Kristine SCHAUER, France
    • Chiara ZURZOLO, France

    REGISTRATION:

    Candidates are invited to download course and travel application forms.

    Please return all completed forms, including two letters of recommendation to hku-pasteur@hku.hk.

    Accommodation (on sharing twin basis) and food (canteen-style) will be provided.
    Travel fellowships (up to 5) will be awarded to the best non-Hong Kong residents.

    The course (MMPH6175) is included in the coursework curriculum for research postgraduate studies of the University of Hong Kong.

    DEADLINE FOR APPLICATIONS: 8 February 2013

    FOR MORE INFORMATION, PLEASE CONTACT:

    Anne LI at +852 2816 8403 or hku-pasteur@hku.hk.
    Check www.hkupasteur.hku.hk for programme updates.

    5th HKU-Pasteur Cell Biology Course on Imaging Host-Pathogen Interactions