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24 Jun 2016

International Call for Applications for a Leader of 4-year research group within the Institut Pasteur in Côte d’Ivoire

Closing date for applications: September 30th, 2016

The Department of International Affairs of the Institut Pasteur is launching an international call for applications for future leader of 4-Year Groups (G4) within the Institut Pasteur in Côte d’Ivoire.
The candidate will be appointed head of a research group for 4 years and will receive start-up funding that includes his/her own salary and potentially that of engineers, technicians and doctoral students, as well as basic laboratory equipment and an operating budget. The candidate should subsequently obtain fresh funding to maintain his/her group on the longer term.
 
Chronic hepatitis, cirrhosis and primary liver cancer (mostly hepatocellular carcinomas), related to chronic Hepatitis B and C infections or other etiological factors, represent a major public health problem in African countries at large and in Côte d'Ivoire in particular. Biomarkers that might reliably indicate the stage and predict the evolution of the liver disease would be of major value for the implementation of the most appropriate and efficient measures for patients' management.
 
The Institut Pasteur in Côte d’Ivoire is a national institute whose missions include public health activities, teaching and research. It is part of the Institut Pasteur International Network that comprises 33 institutes worldwide.
 
Applications are completed exclusively online: http://g4.pasteur-international.org

Contact: Eliane Coëffier
 
For more information see the webpage: http://www.pasteur.fr/en/international/international-network-courses/4-year-group

24 Jun 2016

A trail to a vaccine against Zika and Dengue viruses?

Félix Rey, Head of the Structural Virology Laboratory at the Institut Pasteur in Paris and his co-workers from the Institut Pasteur and the French National Centre for Scientific Research, in collaboration with Imperial College London and the University of Vienna, Austria, have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus. The description of the binding site for these antibodies on the viral envelope, identical for both viruses, could lead to the development of a universal vaccine that offers simultaneous protection against dengue and Zika virus disease. These results were published in the journal Nature on June 23, 2016.

3D structure of the Zika virus envelope protein (red, yellow and blue) in complex with the neutralizing antibody (in green and white). © Institut Pasteur

Structural basis of potent Zika–dengue virus antibody cross-neutralization

Barba-Spaeth G, Dejnirattisai W, Rouvinski A, Vaney MC, Medits I, Sharma A, Simon-Lorière E, Sakuntabhai A, Cao-Lormeau VM, Haouz A, England P, Stiasny K, Mongkolsapaya J, Heinz FX, Screaton GR, Rey FA

Nature (2016) doi:10.1038/nature18938

Read the full story on the Institut Pasteur website.

06 Jun 2016

Summer school in computational biology for infectious diseases, Hanoi, Vietnam 18-25 September 2016

The Computational Biology for Infectious Diseases summer school is designed to provide students, researchers and professionals with basic concepts and hands-on experience in quantitative analyses of high throughput data. The school is organized in 5 parallel thematic groups for 6 days, preceded by 1 day of plenaries and followed by 1 day of review and practice sessions. The trainings will be given by leading experts in their fields, with strong teaching experience for beginners.

More information on www.cbid.asia