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28 Apr 2016

MRC Technology and Institut Pasteur of Shanghai, Chinese Academy of Sciences collaborate on antibody drug development

On March 7th, MRC Technology (Medical Research Council Technology transfer charity, UK) and Institut Pasteur of Shanghai, Chinese Academy of Sciences - IPS-CAS signed a collaboration agreement to develop new therapeutic antibodies from research originating in China.

Monoclonal antibody-based drugs have been established as one of the most successful therapeutic strategies for the treatment of infectious diseases, cancers and autoimmune diseases. “The promise of immune check-point antibodies and broadly neutralizing antibodies against pathogens brings a boom in research and research development across the world, which makes this collaboration all the more significant and important”, said Professor Sun Bing, the Director of IPS-MRCT Joint Centre for Therapeutic Antibodies.

Read more on IPS-CAS website: here

28 Apr 2016

3rd Edition of the Centre Pasteur of Cameroon’s Scientific Days, 28-30 September 2016, Centre Pasteur of Cameroon, Yaounde, Cameroon

Theme: "Emerging and Re-emerging Infections: New findings, Threats and Control Strategies"

In the globalized world, emerging and re-emerging infectious diseases represent major public health threats in coming decades. The 1960s was filled with great optimism: with advances in medicine and the development of adequate preventive measures, we observed a significant decline in infectious diseases. This decline was further apparent by the eradication of some diseases such as smallpox in 1977. However, in the last three decades, we have observed a surge in several emerging and often fatal infections such as HIV/AIDS, respiratory infections (severe acute respiratory syndrome (SARS) and the Middle East Respiratory Syndrome associated to Coronavirus (MERS-CoV)), viral haemorrhagic fevers (Ebola and Lassa viruses), arboviruses (West Nile and Zika viruses), and other zoonotic infection. Conversely, certain infectious diseases including chikungunya and tuberculosis that were already in decline are re-emerging. Multiple factors could favour the emergence of infectious diseases but most cases are related to the evolution of the pathogen, the vectors as well as changes in the host’s environment (climatic, socio-economic and cultural) that affect the ecosystem.

The aim of the 3rd Centre Pasteur of Cameroon’s Scientific Days is to bring together experts from different disciplines (Virology, Bacteriology, Mycology and Parasitology) working on human and animal health, environmentalists, anthropologists, and policy makers with focused discussions on emerging and re-emerging infections. Discussions will be organized under five sub-themes, and each will be approached in a multidisciplinary manner. The purpose is to sensitize stakeholders towards a "One Health" approach in the fight against emerging and re-emerging infections.

Sub-themes:

1. Diagnostic Tools
2. Epidemiology and surveillance
3. Vectors and reservoirs
4. Control Strategies
5. Socio-Anthropological aspects

The symposium is opened to all scientists.Opportunities will be given to companies to display their products in dedicated booths around the conference center.

Abstracts will be accepted for both oral or poster presentation, and may be submitted in English or French.
The abstract submission deadline is May 30, 2016, by e-mail at: jscpc@pasteur-yaounde.org
The deadline for pre-registration is 1 July 2016.

For information and registration: http://www.pasteur-yaounde.org/index.php/en/ or contact: jscpc@pasteur-yaounde.org

26 Apr 2016

Zika virus surveillance

Over 600 researchers and experts are gathering at the Institut Pasteur in Paris for the International Zika Summit 2016 (25-26 April). The speed of the Zika virus propagation requires open collaborations between researchers, the public health community and the public. This meeting aims at providing a venue for open such discussions. The meeting is sponsored by the Institut Pasteur, the Bill and Melinda Gates Foundation and the Wellcome Trust, with organizational support from WHO, REACTing, Aviesan, the European Commission, USCDC and ISARIC.

 Press conference, International Zika Summit 2016 © Institut Pasteur

Zika virus is now present in over 34 countries in Latin America and the Caribbean affecting over 1.5 million people. On Zika virus potential to enter Europe, researchers at the Institut Pasteur's Arboviruses and Insect Vectors Unit led by Anna-Bella Failloux worked with Portuguese researchers (Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa) to assess the vector competence, or virus transmission potential, of four mosquito populations: two populations of Aedes aegypti from Madeira and two populations of Aedes albopictus from southern France. The scientists infected female mosquitoes with Zika virus belonging to the Asian genotype equivalent to that currently circulating in Brazil. The results show that Ae. aegypti transmits the virus more effectively than Ae. albopictus. In Ae. aegypti, the virus only takes 9 days to complete a full cycle and infect the insect's salivary glands, ready to be inoculated into a new host through a bite. In contrast, Ae. albopictus completes the same cycle in 14 days which significantly limits transmission. It therefore appears that tiger mosquitoes in southern France and probably continental Europe are less capable of transmitting Zika virus locally which seems to support a hypothetical scenario whereby transmission is limited to regions in which Ae. aegypti is present.

Read the full news on the Institut Pasteur website: here.

You can read the preprint study on bioRxiv:

Zika virus, a new threat for Europe? Henri JUPILLE, Goncalo SEIXAS, Laurence MOUSSON, Carla SOUSA, Anna-Bella FAILLOUX doi: http://dx.doi.org/10.1101/048454

25 Apr 2016

Institut Pasteur International Network Symposium: “From basic science to biomarkers & tools in global health”, Paris, winter 2016

Online registrations are now open on the website of the Institut Pasteur International Network: From basic science to biomarkers & tools in global health.

This international symposium will be held at the Institut Pasteur in Paris, from November 29th to December 2nd, 2016. It is open to all the scientific community.

The scientific programme will  cover basic, clinical, epidemiological and implementation science topics. It will be built on abstract-driven sessions based on selected oral communications as well as invited keynote speakers. Poster sessions will also be organized.

More details at pasteur-network-meeting2016.org

25 Apr 2016

Research seminar, 28 April 2016: AoE on Control of Pandemic and Inter-Pandemic Influenza and Centre of Influenza Research

The Area of Excellence on Control of Pandemic and Inter-Pandemic Influenza and Centre of Influenza Research are organizing a research seminar on influenza viruses. It will take place on 28 April 2016, 3.30pm, Seminar Room 6, LG1/F, Laboratory Block, Li Ka Shing Faculty of Medicine, The University of Hong Kong.

Research Seminar I
"The Roles of Influenza Viral Polymerase Complex in Virus Replication and Host Adaptation"
by Dr Alex Chin (School of Public Health, HKU)

Research Seminar II
"Genetic and Antigenic Evolution of H9N2 Influenza Virus in Chicken in China"
by Ms Yujuan Chai (PhD Candidate, School of Public Health, HKU)

All are welcome. Download the poster here.

21 Apr 2016

Institut Pasteur: Neuroscience MOOC

A third Institut Pasteur MOOC (massive online open course), entitled "From neuron to behavior", will be available to the public from May 16. Registrations are open via the "France Université Numérique" (FUN) platform.

This MOOC will cover cutting-edge topics in neuroscience research: evolution, development, plasticity and pathologies of the nervous system. The final sessions of this MOOC will also raise the fascinating issue of the interaction between the microbiota and the brain, a rapidly expanding research topic at the Institut Pasteur. Led by Pierre-Marie Lledo, Director of the Neuroscience Department at the Institut Pasteur, this MOOC will feature not less than 26, top-quality international speakers. Language: English.

Find out more at: https://www.fun-mooc.fr/courses/pasteur/96001/session01/about

13 Apr 2016

Malaria: a new route of access to the heart of the parasite

Scientists have just identified an Achilles heel in the parasite that causes malaria, by showing that its optimum development is dependent on its ability to expropriate RNA molecules in infected cells – a host-pathogen interaction that had never previously been observed. Although the precise function of this deviation remains mysterious, these findings open new perspectives for the targeted delivery of therapeutic agents within the parasite. This study, led by Magali Frugier from the Architecture et Réactivité de l’ARN laboratory (CNRS, Strasbourg), in collaboration with Robert Menard from the Malaria Infection and Immunity Unit at Institut Pasteur (Paris), has been published in PNAS the week of 11 April 2016.

Bour T, Mahmoudi N, Kapps D, Thiberge S, Bargieri D, Ménard R, Frugier M. Apicomplexa-specific tRip facilitates import of exogenous tRNAs into malaria parasites, PNAS, April 11, 2016. DOI : 10.1073/pnas.1600476113

Read more on the Institut Pasteur's website.

08 Apr 2016

Last days to register to the MOOC “Epidem” which will start on Monday 11 April 2016!

Launched by Arnaud Fontanet, from the Center for Global Health (Institut Pasteur) and the CNAM (Conservatoire National des Arts et Métiers), the MOOC is open to registration on FUN Platform until April 10.

For 6 weeks, this MOOC will cover key principles of descriptive and analytical epidemiology. The course will also address the main principles of causality and the levels of proof required today to establish the link between risk factors and diseases. At the end of this MOOC, the students will have the keys to interpret scientific articles dealing with these subjects, and will be prepared to pursue specialised teaching in ‪‎epidemiology‬ and public health‬.

Format: 1 video of 10-15 minutes per day for 6 weeks. The course is given in French with English subtitles.
New : Learners will have the opportunity to get an authenticated certificate if they successfully pass the final exam.

Registration on FUN Platform (France Université Numérique, "French Digital University").

06 Apr 2016

The Pasteur Course “Infectious Disease Outbreak Investigation” has started on April 4 in Paris

This intensive 2-week course (4-15 April 2016) is intended for medical and public health professionals involved in field investigations of infectious disease outbreaks.  The course will provide professionals with a thorough approach of the methods of outbreak investigation of emerging and re-emerging pathogens including Ebola Virus Disease, Middle East Respiratory Syndrome Coronavirus, Plague, Avian Influenza subtype H5N1, pandemic influenza, enterovirus 71, and others.
 
This course will cover methods and processes used to detect, investigate, interpret and report on infectious disease outbreaks and include wide ranging topics from preparing to respond to an emerging threat, implementing multi-disciplinary field investigations, analyzing and interpreting results from field studies, to communicating results to different partners.

The course has been set up by Maria Van Kerkhove, from Institut Pasteur Paris, and Malik Peiris, co-director of HKU-Pasteur Research Pole. Dr. Maria Van Kerkhove is the Head of the Outbreak Investigation Task Force (OITF) at Institut Pasteur’s Center for Global Health. The OITF is a multidisciplinary team of Pasteurians located across the Institut Pasteur International Network with experience in field investigations of infectious diseases: experienced epidemiologists, virologists, microbiologists, laboratory technicians, veterinarians, social scientists, clinicians and others who are ready to provide support to the management of and response to emerging and re-emerging threats in countries where Institut Pasteur operates and beyond. Chris Mok, principal investigator at HKU-Pasteur Research Pole also takes part in the Infectious Disease Outbreak Investigation course.

Over the past years, HKU-Pasteur Research Pole has already been committed in organizing educational and training programs regarding outbreaks investigation in the Southeast Asia region. The latest of the 3 international courses "Outbreak Investigation and Acute Response" was held in November 2015 at the Institut Pasteur in Ho Chi Minh, Vietnam.

 

This intensive course is intended for medical and public health professionals involved in field investigations of infectious disease outbreaks.  The course will provide professionals with a thorough approach of the methods of outbreak investigation of emerging and re-emerging pathogens including Ebola Virus Disease, Middle East Respiratory Syndrome Coronavirus, Plague, Avian Influenza subtype H5N1, pandemic influenza, enterovirus 71, and others.

 

This course will cover methods and processes used to detect, investigate, interpret and report on infectious disease outbreaks and include wide ranging topics from preparing to respond to an emerging threat, implementing multi-disciplinary field investigations, analyzing and interpreting results from field studies, to communicating results to different partners. 

- See more at: https://www.pasteur.fr/en/teaching/institut-pasteur-courses/epidemiology-and-public-health-theme/infectious-disease-outbreak-investigation#sthash.kBAUt8E4.dpuf